Special Issue on Dynamic Architecture of Rotary Motor Proteins and Their Cellular Assemblies

Submission Deadline: Jun. 10, 2020

This special issue currently is open for paper submission and guest editor application.

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Special Issue Flyer (PDF)

  • Special Issue Editor
    • Shahid Khan
      Molecular Biology Consortium, Lawrence Berkeley National Laboratory, Berkeley, USA
    Guest Editors play a significant role in a special issue. They maintain the quality of published research and enhance the special issue’s impact. If you would like to be a Guest Editor or recommend a colleague as a Guest Editor of this special issue, please Click here to fulfill the Guest Editor application.
  • Introduction

    The issue will cover the constraints imposed by the common rotary design of important biomolecular assemblies such as the ATP synthase, calcium-calmodulin dependent kinase II (CaMKII), DNA helicase, archaellar and bacterial flagellar motors. Multi-subunit interactions in these assemblies have evolved to tune cooperativity to specific functions. Remarkably, subunit stoichiometry in a number of these assemblies has evolved to vary for either dynamic adaptation to environmental stimuli or to increase diversity for colonization over a broad habitat range. An important consequence is the ability to remodel the intracellular or multi-cellular architectures in which they participate – mitochondrial membranes (ATP synthase), actin cytoskeleton (CaMKII) or biofilms (archaellar and bacterial flagella). Innovative microscopy methods, computational image analysis algorithms and theoretical models have driven investigations into the design principles of these rotary machines and the architectures that they regulate. There is a need to develop a common language and toolkit between the communities, working by and large as autonomous modules, on specific experimental systems. Exciting recent advances in cryo-electron microscopy and single molecule spectroscopies together provide an atomic level characterization of conformational ensembles that provide powerful constraints to refine and develop theoretical simulations and models. This issue will seek to achieve this aim by bringing together apparently diverse systems themed on their common architecture and dynamics.
    Aims and Scope:
    1. Energy transduction
    2. Protein allostery
    3. Multi-subunit assemblies
    4. Cellular remodeling
    5. Multi-scale simulations
    6. Nanoscale biophysics

  • Guidelines for Submission

    Manuscripts can be submitted until the expiry of the deadline. Submissions must be previously unpublished and may not be under consideration elsewhere.

    Papers should be formatted according to the guidelines for authors (see: http://www.ejbiophysics.org/submission). By submitting your manuscripts to the special issue, you are acknowledging that you accept the rules established for publication of manuscripts, including agreement to pay the Article Processing Charges for the manuscripts. Manuscripts should be submitted electronically through the online manuscript submission system at http://www.sciencepublishinggroup.com/login. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal and will be listed together on the special issue website.

  • Published Papers

    The special issue currently is open for paper submission. Potential authors are humbly requested to submit an electronic copy of their complete manuscript by clicking here.

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